Went against a Blitzcrank and Singed bot... needless to say we were destroyed bot (><)

Grab+flip = dead

morgana+kennen, or kennen+amumu, or gailo+pantheon<-- most fun :P

Zilean/Hecarim. More speed for hec...means more damage.

Viktor/Veig...not saying as a lane partners...but on the same team, man these two are pretty OP. You be best to hide your mages. Veig lays down his stun and summons the comet, viktor comes in and places his stun for an annoying doube stun. Veig ults and blows up their Ap, Viktor ults and blows up the whole team.
(i done this, it was fun)

yorick/any AD carry.

:Leona/Riven is a good one, me and my friend had a 12 win streak with it.

Galio + Nunu

A really good one is Wukong top/jungle and Fiddle Mid.

Renekton taric is a hilarious bot lane

From what I've witnessed/played:

Blitzcrank/Vayne is one of the best lane combos in the game.
Alistar/Ashe (I think Ashe or Vayne is the best carry for Alistar)
Janna/any ad carry

Break the meta:
Rammus/Renekton(is insane)
Lux/Morgana(you'll never escape)
Blitzcrank/Riven
Leona/Xin Zhao

You also need to pick stuff u want to do. Kill lanes are always a blast and can really mess up bot lane which is what ppl are telling u to do but if u guys play like pusy cats then it wont work

Blitzcrank and Caitlyn I've found to be an effective (and meta-friendly) combo. Blitzcrank hides in the bushes and pulls somebody onto a Cait trap, auto attacks once, then resets his timer to knockup. All the while Cait can drop another trap in front of that enemy and auto attack the entire time.