WELL I am GLAD you guys only get it once in a blue moon, last game, playing Urgot, it happened at LEAST 12 times. And no you don't just sit there, when enemies are in the lane and you are there you chase them in auto attack, kinda like how my second time dying I ran into their tower chasing him while clicking frantically to turn around with no luck. It isn't anything but this game, I play Starcraft II, no problem, any other game is fine, but it is happening more and more for me on LoL. Like everyone else says, I can type to my team and try and tell them it isn't my fault but that is about it. When it happens it feels like the game is telling my mouse to "screw off." It is very random. You can be fine for a few minutes, but then it kicks in and you can't control anything with the mouse on your character. you can move the mouse around and look around you like the mini map and stuff, but you can't click on anything, that's basically what is is, but it seems when it happens as well I can't cast spells with QWER either... It is weird.