IMO, the correct way to deal with this is to remove the Silver Bolts single target restriction and let Vayne stack it on multiple targets instead of losing it the way she does now.

Then it would be like every other on-hit effect instead of following arbitrary rules of its own.

If that makes it too strong, then it should be nerfed to be brought in line with other on-hit effects like Blighted Quiver and Toxic Shot.

I notice how this item's introduction coincided with the removal of Maldred's Bloodrazor. Hurricane alone would have made MBR a great item. If Hurricane was coming, there was no reason to remove MBR because Hurricane's very existence makes MBR good.

Thanks for the list. Curious about any interactions with Twitch's ult, though.

And then you'd have to nerf Vayne because Silver Bolts' balance depends on the fact that if you disengage from Vayne, she will require additional work to Silver Bolts to trigger on a teammate.

It'd also destroy Vayne's feel of a single target assassin - so I can't agree with you here.

Am I crazy, or does this item seem insanely powerful?

You missed Lux in that list, (i know this item would NEVER be viable for her anyway) but would it detonate her passive on multiple enemies that have it on them?

Are you afraid this might be a bit ridiculous with Urgot's passive?

I'm curious about the effects of thornmail and similar abilities (ie Fiora's Riposte). Hopefully this gets seen.
If I'm shooting Target A as my primary, but there's a Target B next to him with a thornmail. Do I still take the thornmail damage?

Oh good, you've found a way to make Teemo even more obnoxious.

Isn't that just suboptimal coding?

Oh yes, Lux should detonate her passive on multiple enemies that have it - but Hurricane would be awful on her. XD

Yes.

No - It's just a special case because Vayne's silver bolts has a very specific 'consecutive hits or else reset' mechanic.