Originally Posted by iMaelstrom
I have a Razer Naga and I don't even use the extra buttons for this game. There is literally nothing to bind that would be beneficial. You are deluding yourself if you think moving your thumb around on your mouse is faster than keeping your other hand on 'QWER' (or whatever setup you run).
I have a Razer Imperitor and I love the extra buttons. But, you are correct, League doesn't really have a use for them.
Maybe I should set a thumb button to "B" just because I can.
But in OTHER games, I can hardly imagine living without my thumb grenades.