that question makes no sense to me, Eiko. The purpose of any applied knowledge is simply in creating practical results. On the one hand we have Magic; The ability for mages to enact a huge array of practical results through such things as mana energy and runecraft. On the other hand we have Technology; The ability for scientists to enact a huge array of practical results through such things as kinetic energy and voltage.
I expect runeterran denizens find the two difficult to distinguish from eachother. Both harness quirks discovered in how the world works. For us as players, the difference is merely that magic isnt real. mana isnt real. runes arent real.
If you are a character in the story right now, with how undefined the differences are, science could be thought of as just another branch of magic, or magic as just a branch of science. Why would it matter?
I guess one reason that comes to mind for the separation is that, perhaps, magic all ties to the same source element, unlike how science is a hugely unspecific term that can apply to nearly anything. Chemical science, Aeroscience, ect.. Talking about 'magic' would just be a way of talking about things that come of the source, and you could be further specific by talking about Clairvoyance or Hextech, putting those on par with Medicine, and you could be Even Further specific by talking about sub-disciplines thereof, Corpsecrafting vs Heart Surgery, and finally you arrive at supreme specificity: A technique of Corpsecraft for threading necro-essense through technomantic arteries vs A technique of Heart Surgery for installing an artificial valve.
Other than that im at a loss. ;D