If your teammates dont need it, be sure to grab blue buff because 25% cdr is absofruitly wonderful on vlad.
Also one of the biggest mistakes I see vlads doing is being too aggressive early, sure you can harras at no cost with Q, but the high(ish) cd and not great damage means your likely to take more damage than you put out against a good player. By all means Harrass if its safe but just because you have pool doesnt make you invincible :P, many vlads I have killed because they keep trying to harrass early with Q and I just drop back take a hit, hit em back and wtach as they lose 200hp from creeps everytime.
One more thing..always keep an eye on your enemies items, if there is a MBR or DFG in the works this is high time for some MR. Force of nature is costly but is hugelyy benefical for vlad because of the scaling regen, some much needed movespeed (vlad is very slow) and of course the high MR.
Funny story I played a normal game a few days ago as veigar and the enemy team had a vlad. He had exactly the bas MR of 30 and I had sorc boots + 10mpen in runes. By late game I had over 500AP and a DFG. Vlad had close to 4k hp. Needless to say I was doing just over 50% of his hp in 1 hit with no resistance. 1shot for over 2k damage is pretty lols<<<dont be that vlad.