I logged on my account today after purchasing the Rune Page Bundle for 2600 RP and I'm missing all my runes at the moment, I mean literally everything is missing and wiped clean from my account. Does anyone know why this happened? Are there any solutions to this? I already submitted a support ticket in hopes that they can respond soon.

As long as you have submitted then the only thing you can do is wait. Aparently there was a inventory issue where some people have lost their runes they should be able to get your runes back to your account,
http://na.leagueoflegends.com/board/showthread.php?t=1697766

Mmk, this helps a lot. Thank you.

Submitted a ticket and still no reply ;___; can any red post on this?