Mitigation is a logical choice for Vladimir, however, I'm not entirely solid. First off, buying mitigation simultaneously means you're not spending money on getting more damage (which will also give more eHP by virtue of gaining more HP). Second, your build costs a significantly greater amount of gold, which means it cannot be compared at face value. Please check out the FAQs section in my guide for whether or not I believe CDR is worth it.
I only take issue with Soul Visage and Abyssal Scepter in this build. Abyssal because Visage will grant the same amount of magic penetration for far less cost and because it is not that efficient of an item. It, however, can be efficient under the right circumstances -- just watch the enemy MRs. As for Soul Visage, see the FAQs section of my guide.
Take cleanse because they are going to ignite you? Cleanse doesnt remove ignite anymore.
And SPIRIT(not Soul) visage has nothing to do with Magic Pen i dont understand why you are comparing it to a Scepter. Spirit visage is 100% built as an early game Vlad item, there is not 1 stat on there that is not useful.