I am having an awful day and decided I'd go back to trying to get enough IP for Shyvana, so I started a bot game up.
I have a usb headset that has sort of a loose plug. It's known to wiggle free and Windows does a pretty good job of switching my audio to the speakers when that occurs.
Except in LoL, apparently. I shifted and it pulled loose and the entire game I played was bugged in various ways.
First Blood had just happened ingame. The notification never went away. Anything that'd have a sound cue was delayed by several seconds.
http://pastebin.com/LrrNNvQX This is the game log.
League of Legends Community