I have been having the same issue, sometimes I can play a few games without a problem, sometimes the screen turns black, sound starts looping and the only way to get things back to normal is to turn notebook off the hard way.
I have tried with lowest graphic settings
Re-installing lol
Fromating
Updating drivers
Cleaned the fans and checked temperatures, not the issue.
No other game gives me this problem
Problem has been consistent in windows 7 and 8.
Video card: gtx 285m
6gb ram ddr 3
Processor i7 1.73
This started happening after an update, I don't remember which one.