I'm a level 21 character who has not used any runes up to the point because my friends told me to hold off for Tier 3 runes and have about 20,000 IP to spend on runes.
The roles I struggle at the moment are pretty much carries (AP/AD) and junglers.
Therefore when I play Solo Queue, I like to play characters who have better survivability (Whether they have sustain or the builds for them lean towards building items that increase HP).
Right now, I would say my best/favorite roster of champions are:
From what I have read about the runes, it seems I should lean to Armor and Magic Resistance.