A huge mass of people could overwhelm anyone, Pantheon and Darius included.

Plus, although the giant shield would be very useful the spear can only kill one person at a time.

Darius has a huge axe, and would kill tons of people until the mob of humans closed the distance and restricted his movement, and then just tear at him.

People like Karthus, Mundo, Alistar, and Syndra would be much better, since magic=OP and Mundo and Alistar would be much harder to swarm since they are so much larger and stronger.

I feel awful picturing the Darius fight

Shyvana... uh... can punches and fists break dragon scale..?
Fire aura... sustain on dragon form... yup

Fizz

Jump over them, coat them in eel gel and then poke them

Also, SHARK!

Hmm...Well Orianna's Ball hurts hard, but I guess with enough people even she would be ovewelmed.

Ezreal can easily one shot anybody.

Riven's sword gives her the edge in long ranged melee combat.

Xin Zhao is Xin Zhao. Nuff Said.

Sona doesn't need to kill em, her music makes em stop on their own.

Corki.....well lets list the facts.....he has a machine gun.......he can create a trail of fire......he flys......i dotn see this ight going well for the unarmed land based humans without fire resistance......

Unarmed? Not too many, Lux is rather frail physically. Let's say a nice round 30, if she can't lore!stealth.

Trundle heals every time he noms someone.

Well Malzahar has a lot of a AOE and DOT and voidlings help so id think he would be fine for a while