After taking a little bit of time, I've come up with a very fun build on Miss Fortune that looks like it will wreck a team pretty hard, and I figured I would share it and see what my fellow PBE users though. I don't even mind if ya use it for yourself (or I wouldn't be posting it!)

The full build goes as follows:
Furor Berzerker's Greaves
Black Cleaver
Blade of the Ruined King
Runaan's Hurricane
Bloodthirster
Bloodthirster/Guardian Angel

The above build will grant you up to over 400 AD, ~1.9 AS with Attack Speed runes and Impure Shots active, up to ~4x% Life Steal, and up to 25% armor reduction on a full team. You hit R and reduce an enemy team significantly, and then you start auto-attacking. Each auto will deal ~200 damage and 4% of a target's max health as physical damage to the champion standing next to your target. Oh, and did I forget to mention, each auto-attack is boosting your Movement Speed by 12%? So, if you keep Strut active, you'll have like 500+ MS!

Of course, the obvious flaw to this build is that there's no Crit. The goal is not to blow up one target at a time, but to annihilate an entire team all at once, mostly by getting a Penta-Kill by the Triples (think about it for a second, and that makes perfect sense).

Let me know what you guys think about my AoE Queen build! If you think another item would be better than what I have listed, then please let me know! Just keep in mind, the main goal is not to blast out one target, but to take down an entire team at once.

I'll test it out tomorrow!

If you're going to do Runaan's Hurricane + Blade of the Ruined King, you're better off doing so on Kog'maw, whose W applies on Hurricane. Black Cleaver is better taken on a Bruiser while AD carry takes Last Whisper, since BC can't stack but its armor reduction benefits your team. Also, if you get caught, you're essentially dead, since you'll have no movement speed.

Your E would only be useful as a slow for advancing/escape. You shouldn't depend on Strut to get away. All they have to do is touch you once and you aren't the longest range in the game. Furor works as an advancing effect and nothing else. 2 seconds what decays fast is a really, really short duration. Assassins will have a field day jumping on you if you lose map awareness.

The core of your build is:
Black Cleaver
Hurricane
Bloodthirster

That is all fine. It is actually worth it to stack two BCs together. You double the CDR and Armor Pen. You max the shred stacks in two hits rather than four. This means that your ult maxes out after the first 25% rather than after the halfway point. Mana can be an issue with this build if you are trying to be a caster.

Sounds like S2 Tiamat MF.

IMO she seems useless with out an IE

too good

i had fun with graves and a hurricane. between that, q, w (lol damage but still), and r... was a pretty potent aoe setup

cleaver vs whisper could be debatable on him, i LOVE the stats on cleaver, but for the armor pen last whisper prolly wins out for aoe purposes, since he doesnt have a way to stack it on EVERYONE too fast, unless you get 2 cleavers, which is meh. it works, but just feels like you could do better imo