The play pattern that I have success with is using Q to harass in lane without focusing on getting the stun off. I usually only pick up a kill pre-6, without jungle help, if my enemy makes a mistake of staying after I land 3 Qs. If you have a jungler that is paying attention to your lane you can utilize that to score a kill before you're 6.
For runes I usually use mana regen per level yellows, spell pen reds. I then vary between flat AP quints/blues and MS quints/MR blues.
build is most frequently: boots+3 pot -> double dorans -> sorc shoes -> Haunting Guise -> death cap.
Just curious, I haven't had enough time to play SR that much recently and Dominion/Aram aren't those most...accurate testing sandboxes.