Crazy Stealthy Assassin

Q-Deceive
W-Decoy
E-Cutthroat
R-Destiny

He would be a high mobility, Shaco-like carry killer.

Cheater, the OP

Q- Arcanopulse
W- Living Shadow
E- Event Horizon
R- Curse of the Sad Mummy

Usain Bolt, the Unstoppable Flash

Vayne passive
Q- volibear's charge
W- teemo move quick or blitzcrank's overdrive
E- hecarim's charge
R- yi's highlander

for summoner spells, get ghost and flash

The Initiator
I'M COMIN' AT YOU BRO

Q - Amumu Bandage Toss
W - Katarina Shunpo...wait thats not her W who has a pull on W? put that here...
E - Leona Zenith Blade
R - Akali Shadow Dance

Completely useless after he/she Initiates.

Q:Fiddle
W: TF
E: Vayne
R: Tryn
Pass: Voli

Idk, something i thought I would like to see play out for a day or so haha
(AD melee btw)

trolol qwer

Q melee = Shen Vorpal blade
W melee = Riven Ki burst
E melee = Diana Moonfall
R melee = Jayce Mercury cannon (change from melee knives to throwing knives)

Q ranged = Tristana Rapid fire
W ranged = Vayne Silver bolts
E ranged = Zyra Grasping Roots
R ranged = Mercury hammer (change from throwing knives to melee knives)

Xeralee Ryzerdinger, The Magus Degenerate

Q - Nidalee's spear chuck
W - Xerath's Locus of Power
E - Heimerdinger's grenade
R - Xerath's Arcane Barrage
Passive: Ryze's CDR.

HIDE YO KIDS, HIDE YO WIFE

q rocket grab
w headbutt
e fling
r dragons rage
first you pull them, then u fling them behind you, then you head butt them further in that direction, then you kick them even further.
they thought you were diving their tower, 3 seconds later they r under your tower.