I really think it would be a great idea if Riot would make an option to flip the HUD for Purple team. It seems to me that having the bottom portion of your screen blocked off by the HUD is a severe disadvantage in 5v5. 90% of the time you are moving in the direction of the HUD, which blocks a large portion of the screen. Your opponent, however, is coming at you with almost nothing blocking their visibility. This gives Blue team a distinct advantage in poking because they can see Purple on the edge of their screen before Purple can see Blue. And in a game where range can mean everything, that small distance becomes a huge boon to Blue team.
My solution is to make a flippable HUD. Put the Champion Stats, Mini Map, and Spell Bar at the top of the screen for Purple team. This will give both teams a completely even playing field and will negate any potential advantage of being stuck on one side of the map instead of the opposite side.