We are both in college and she may as well live with me at this point. I spend plenty of time with her, take her out and even cook for her, but she still gets upset when i play LoL for a few hours with my friends.
GD wut do!?
Edit: I've tried to get her to play, but she views this as a very childish game. Pffft, women.
Edit #2: Whenever I do play I prefer to play with my with friends (I tend to stay away from Yolo queue) and I make sure to at least offer her the other half of my headphones so she can join in on the conversation (which she gladly accepts most of the time). Meh, maybe I am just an uber a*****e and I'm just being dense as usual.

Get her to play too.

Give her the D.

You're in college. Drop the trifling lass and acquire STI.

Teach her how to play. If she has no interest in joining you, then she has no business getting mad when you play.

Just include her, simple as that. Girls like to feel apart of something... lul...

Talk to her...? See why she doesn't like it. Try to explain that you feel like you spend plenty of time with her, and that there shouldn't be an issue if you spend a few hours with your friends.