This is a post for working linux clients. Hopefully this helps someone install and use LoL on Linux OS or take a step foward to an official client.

Known Bugs-
Mini Map Flickering
Low FPS

Resolution-1920x1080
Running on Lowest Settings

wine version=
1.5 amd64

wine ppa=
http://ppa.launchpad.net/ubuntu-wine/ppa/ubuntu

Wine Global config=
autodetect drives
windows xp
allow window manager x2

Winetricks=
dotnet40
remove_mono
vcrun2005

uname -a=
Linux data-desktop 3.2.0-37-generic #58-Ubuntu SMP Thu Jan 24 15:28:10 UTC 2013 x86_64 x86_64 x86_64 GNU/Linux

lspci=
00:00.0 Host bridge: Advanced Micro Devices [AMD] nee ATI RD890 PCI to PCI bridge (external gfx0 port B) (rev 02)
00:02.0 PCI bridge: Advanced Micro Devices [AMD] nee ATI RD890 PCI to PCI bridge (PCI express gpp port B)
00:04.0 PCI bridge: Advanced Micro Devices [AMD] nee ATI RD890 PCI to PCI bridge (PCI express gpp port D)
00:05.0 PCI bridge: Advanced Micro Devices [AMD] nee ATI RD890 PCI to PCI bridge (PCI express gpp port E)
00:06.0 PCI bridge: Advanced Micro Devices [AMD] nee ATI RD890 PCI to PCI bridge (PCI express gpp port F)
00:07.0 PCI bridge: Advanced Micro Devices [AMD] nee ATI RD890 PCI to PCI bridge (PCI express gpp port G)
00:09.0 PCI bridge: Advanced Micro Devices [AMD] nee ATI RD890 PCI to PCI bridge (PCI express gpp port H)
00:11.0 SATA controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 SATA Controller [AHCI mode] (rev 40)
00:12.0 USB controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 USB OHCI0 Controller
00:12.2 USB controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 USB EHCI Controller
00:13.0 USB controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 USB OHCI0 Controller
00:13.2 USB controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 USB EHCI Controller
00:14.0 SMBus: Advanced Micro Devices [AMD] nee ATI SBx00 SMBus Controller (rev 42)
00:14.2 Audio device: Advanced Micro Devices [AMD] nee ATI SBx00 Azalia (Intel HDA) (rev 40)
00:14.3 ISA bridge: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 LPC host controller (rev 40)
00:14.4 PCI bridge: Advanced Micro Devices [AMD] nee ATI SBx00 PCI to PCI Bridge (rev 40)
00:14.5 USB controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 USB OHCI2 Controller
00:16.0 USB controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 USB OHCI0 Controller
00:16.2 USB controller: Advanced Micro Devices [AMD] nee ATI SB7x0/SB8x0/SB9x0 USB EHCI Controller
00:18.0 Host bridge: Advanced Micro Devices [AMD] Family 15h Processor Function 0
00:18.1 Host bridge: Advanced Micro Devices [AMD] Family 15h Processor Function 1
00:18.2 Host bridge: Advanced Micro Devices [AMD] Family 15h Processor Function 2
00:18.3 Host bridge: Advanced Micro Devices [AMD] Family 15h Processor Function 3
00:18.4 Host bridge: Advanced Micro Devices [AMD] Family 15h Processor Function 4
00:18.5 Host bridge: Advanced Micro Devices [AMD] Family 15h Processor Function 5
01:00.0 VGA compatible controller: Advanced Micro Devices [AMD] nee ATI Tahiti XT [Radeon HD 7970]
01:00.1 Audio device: Advanced Micro Devices [AMD] nee ATI Tahiti XT HDMI Audio [Radeon HD 7970 Series]
02:00.0 SATA controller: ASMedia Technology Inc. ASM1062 Serial ATA Controller (rev 01)
03:00.0 Ethernet controller: Intel Corporation 82583V Gigabit Network Connection
04:00.0 USB controller: ASMedia Technology Inc. ASM1042 SuperSpeed USB Host Controller
05:00.0 USB controller: ASMedia Technology Inc. ASM1042 SuperSpeed USB Host Controller
06:00.0 USB controller: ASMedia Technology Inc. ASM1042 SuperSpeed USB Host Controller