Ap Sion wouldn't be able to kill thresh, cuz one auto from thresh would eat up the shield and plus damage. Funny thing is that this topic is about stacking impossibilities on top of the same impossibility. Thresh's bonus armor and AP caps at 500,025 (99.98%), and even with maximum armor pen you would only take it down to 99.96%. And Vayne would get Thrashed by all 4 of these guys. At point infinity each of these guys do so much damage that Vayne would not be able to kite for the duration that they can survive. It would take Vayne 24 auto attacks to kill Thresh or Sion in which one hit from one of these guys would kill her; Thresh's armor is so high that her Damage does no damage making her completely reliant on the true damage. Even with max attack speed, Vayne would require 10 seconds to kill any champion with an enumerable amount of health or armor. Sion stun auto kill. In Nasus case, he does so much damage with Siphon at this point that he could literally stack 5 armor items to tank her physical damage. Veigar stack health and armor, Q kill.