as said, I am a left-handed person. My mouse is the Razor DeathAdder Left-Handed Edition.
Now I have a problem. My mouse is on the left side of the keyboard, but I use "left click"" and "right click" like a right-handed person. So left click and right click were interchanged in LoL. Thus I downloaded the input.ini data by Riot to solve the problem. And it worked perfectly, except one fact: I can not change the keybindings when I'm in a game. No matter what I wanted to change, my left Mouse click is now the key that I wanted to change.
For example: I want to change my Q to smartcast Q, so I just have to press Q to cast spells immediately. But after I changed my settings, I smartcast my Q spell now with my left click.