I have skimmed around, and found just one post of another person having this problem, which was not addressed by a red at all....

A LOT of the time when I go to change my key bindings, the game just freezes. Not sure what to do about this, it's starting to have a huge impact on the game as to I miss out of the first 2-3 minutes of these games.

Also, for about the past week or so, I have had my PC just completely turn off while playing LoL. Never happens any other time, it's not a GPU/overheat problem as it doesn't do it with more intensive applications... I can't figure it out. Thanks.

Same problem here. I've 2 laptops and it happenned to me in both. PLEASE Riot fix it ASAP. I'm losing ranked because of this problem.

Any injections or macros running?