I have lost track of the mouse pointer a couple of times, especially when there's a lot of action taking place. As a gamer I cannot remember the last time this happened to me in a game.
I suggest a thicker outline and/or more contrast in the color (the gauntlet is nearly the same color as the terrain tiles).

On the note of making things more visible.

perhaps add that same outline element to heros in large fights/packs as well, which would take click priority if your on top of a mob, because i've missed spells in that situations.