Originally Posted by Hyfe
Champs that can absolutely demolish Nasus in the lane if played properly:
literally every ranged DPS (especially Cait, Corki, Ez, Kog, Teemo, Vayne)
TLDR: All ranged carries, most casters, most energy champs, the hyper-aggressive bruisers (Garen, Ren, etc). The only champs that don't actually beat Nasus in lane are other champs that want to passively farm (Galio, Irelia, etc).
Some of those are the easiest to farm against as Nasus..... coming from a Nasus player. He's one of the best solo top champs in the game. All you need is 1 point in SS and no matter how hard they push, if you level your spirit fire and take some early mana/regen..... You can keep anyone off your turret. If you level it up correctly, you can 1 hit minions.
To stop him from farming his Q is either a heal spell, or blind. But a good nasus will just wait for the right moment. If he grabs sheen, a heal isn't going to stop you. Teemo's blinds are unreliable.
My point isn't about who's better skill set. It's about the opportunity to farm as we all know that Nasus is scary when well farmed late game. Solo top lane with a good Nasus = Easy money. You will get annoyances and issues. But good coordination with your team when you need help or to do well last hitting under turrets is the main thing. A good Nasus can farm well no matter the annoyance. If it requires a nasus to lose a little XP to not giving them much more gold for a safe position, they will do it.
EDIT: Didn't mean to quote you Hyfe, was only for a few champs, not all.