And then you ignore everything the last person said.
Vamp scepter? Lol, he must be trolling.
Runes are fine, MR,Armor ARP, i'd probably get Phys damage runes but im lazy about last hitting.
Get your cloth 5, don't do vamp scepter lol, it takes 4 seconds between the time he activates it until he can burst it, so destroy it before then and you won't take damage, if he's going AD then his shield won't ever get too high of HP to break it, and his stun wont deal too much damage because he isnt leveling it.
If he activates it and waits to run in, just back off for the remaining 5-6 seconds, he'll blow up on the minions and you can auto attack them to restore any health you are missing(dont get hit by the explosion) and then be aggressive on him.