I go 9/21/0 masteries, and tanky runes, with the exception of two MS quints and mpen marks.
In game, I build Tanky AP and am usually bottom lane. Very few champions give me any trouble (including Yorick), but some can be quite the challenge (Soraka, Mordekaiser, Graves).
By the endgame, it's usually best if someone switches with me, because in most games I become nigh unkillable and Maokai's teamfight presence is invaluable.
Even if they don't, I take ghost for a reason. There are times when I can ghost to top, destroy a teamfight, and recall to my point before my opponent at bot has started to channel. I love this tree.
(And I have the charred skin, so I don't particularly mind being on fire. :P)