Yeah, I've been having the "getting hit from across the room" feeling from both the lizard and golem neuts a lot lately. Simply attributed it to network latency and server-client hiccups / dropped packets.
I think this oddity may be related to the network latency and position-tracking desync I've been observing over the past few days (last night in prime time EST especially).
I owe a number of recent deaths to what I call a "ballerina problem"; because the LoL game server is not delivering updated information to the LoL game client as quickly as is expected, running into a minion or two can often cause your champion to become a twirling, panicking idiot.
A collision between minion and champion is reported late by the server, so the champion gets "adjusted" back to where he/she is supposed to be client-side (ie. runs back to the point of the collision just to make sure it's displayed properly). This can result in four to five second interruptions as the server and client try to negotiate proper pathing information while the user clicks furiously and tries to figure out what the HELL is going on. During which time, it's open season on your ass for towers and champions with ranged attacks or abilities, or Ghost/Flash.
In retrospect, I probably owe more deaths to this problem than to genuine gaffes on my part, in my last two or three normal games. Consequently I've learned to give both friendly and enemy minions a freakishly wide berth. And not to click somewhere across the map as a run-to point; the champion will sometimes just stop, run back to an arbitrary position, and sit there motionless.