Just a random question, I know they don't have much in common lorewise, but they're both from the shadow isles and Evelynn doesn't seem specifically aligned with Hecarim/Morde/Karthus/Yorick.

Do they know each other? Do they like each other? They seem like they'd get along fairly well, what with having a rather disturbing fascination with hurting people for personal gain.

I doubt they care much about each other

They are just from the shadow isles and thats about the only similarity. Its like you living in the same city as some random person you dont know.

The closest relationship I can think of for them would be rival killers.

They both seem too cold to really be friends.

That said, according to the old Journal of Justice Evelynn dated Twisted Fate until she dropped him, so she is at least capable and potentially willing to be friend- though I don't intend to imply another romance.

Elise, on the other hand, gathers cultists and murders them like lambs to the slaughter- I think any bonding from her is purely artificial and for her own interests.