Originally Posted by PatrickStar
Doran's is not needed as a starter for Nasus. Your Q with Spirit Fire should heal you tons. I believe MP5 runes break even at level 5, which means flat runes only had the advantage for the previous four levels. Also, the blue and yellow MP5 runes will allow you to completely skip Chalice, allowing you to get that early Trinity or GA or any other tank items. Make sure you prioritize getting TF last, if an even game should occur.
Ring is mp5 and ability power, which gives me that slight edge of harassment and some much needed mp5 (since I'm only running flat yellows, it helps a lot) along with enough health to compete with fellow tanks (i.e. tanks/tanky dps with decent laning, for example Garen, Mordekaiser, Shen) so I like it. That's just me.
Also, I never, ever, ever, ever get Chalice. Waste of money.