Originally Posted by Nethervoid
Honestly, a good Twitch is going to get his through positioning and cleanse. There really isn't anything you can do about it but make sure he only kills 1 champ and not your entire team.
Vs a bad/mediocre Twitch, stop your team fight and focus fire him if he's in range.
A good Twitch won't be in range, and he won't pop until a lot of your cc has already been used. In this instance, your entire team needs to move away from the Twitch. Spread out, backup and he can't ever take more than one of you.
Despite all the new champs, a properly played Twitch is THE best killer in the game. Look at LOL database, he's #1 in kills per game and by a substantial margin. If you hold him to under 10 kills in a game your team has done a good job and have given your team a chance to win.
Twitch is also a team based champ, if Twitch is waiting till late to pop, target the support champ that protects him, you may bait him into a positioning mistake. If twitch overextends by a hair, he dies instantly.
The good news is, very few players play him properly.
A decent way to counter twitch start game is to place wards around the area but thats about it, a good twitch that isn't stingy will buy his own wards and pop your wards in the area to keep himself safe, as of late game, oracles don't really help since a good twitch will spray and pray from out of oracle range and try to kill your oracle holder or atleast make him retreat so he can freely then pop invis in the team fight, if he sees that he can't do either then he will just stay out of range and keep spraying whatever he can get his hands on then back out into the middle of his team to be safe and wait for chances to slow and finish off remaining enemies.