Same issue, worked fine yesterday wont load today. I've tried every listed solution in the toolbox, and I've re-installed (which was a pain seeing as how the game download link is broken so i had to scour the net for a mirror)

I dont know what would have changed between yesterday and today - if this is all on riot's end i would like to know so i can stop messing around with my computers settings before i mess something else up.

To anyone else who reads this thread, I'm almost 100% certain after wasting a whole day trying to fix this issue that its Riot's fault and they just aren't telling us. With the amount of complaints I'm seeing, and knowing that the download link for the game is offline, i'm assuming Riot's computers are completely fubar'd

My solution to the RADs error issues is to go do something else and try again tomorrow.

I am also disappointed. Been waiting for a week to get an answer or an solution from Riot but they are just ignoring this problem.
I've tried everything they instructed in other threads and tried all the recommendation but all were failures.

Just randomly having same problem. As many others complete clearing of all game files and re install does not help. Here is the kernel.log
"
( USER)[02:40:05.245] RADS::UserKernel::Application::Run: Riot Application Distribution System (c) 2010 Riot Games (version 1.0.0.226)
( USER)[02:40:05.246] RADS::UserKernel::Application::Run: Running at 02:40:05 on 09/01/2011
( DEBUG)[02:40:05.246] RADS::UserKernel::Application::Run: Command line: "updateandrun lol_launcher LoLLauncher.exe"
( DEBUG)[02:40:05.246] RADS::UserKernel::Application::SelfUpdate: Executed from root folder with correct name, not an update.
( DEBUG)[02:40:05.246] RADS::Common::HTTPConnection::HTTPConnection: (http://l3cdn.riotgames.com)
( DEBUG)[02:40:05.247] RADS::Common::HTTPConnection::Connect: (http://l3cdn.riotgames.com)
( DEBUG)[02:40:05.248] RADS::Common::HTTPConnection::GetFile: ("/releases/live/system/rads_user_kernel.exe.version", "C:/Riot Games/League of Legends/RADS/temp\TMP600B.tmp", RETRY, 0x00000000)
(WARNING)[02:40:05.250] RADS::Common::CiderUser32::CiderUser32: Failed to load TGIsFullscreen, CiderUser32 not running
(WARNING)[02:40:05.250] RADS::Common::CiderUser32::Create: Failed to startup CiderUser32, not on a Mac
( DEBUG)[02:40:05.330] RADS::UserKernel::Application::SelfUpdate: Up to date.
( DEBUG)[02:40:05.331] RADS::Common::HTTPConnection:isconnect: ()
( DEBUG)[02:40:05.339] RADS::Common::LocalFileSystem::FindFiles: (C:/Riot Games/League of Legends/RADS/temp/TMP*, 0x00000000 , 0x00000000)
( DEBUG)[02:40:05.347] RADS::UserKernel::KernelThread::KernelThread:
( DEBUG)[02:40:05.347] RADS::Common::Cider::Cider: Failed to load TGIsFullscreen, Cider not running
( USER)[02:40:05.347] RADS::Common::Cider::Create: Running on Windows
( DEBUG)[02:40:05.347] RADS::UserKernel::KernelThread::ThreadProc: ()
( DEBUG)[02:40:05.348] RADS::User::PandoManager::start: launching Pando
"

bump

I knew Riot was the problem, I'm glad it wasn't my computer.

bump

Go into your LOL folder look for

Rads_lol_launcherlog2 delete it and fire the game up worked for me hope this helps

same

same problem! help me.